Welcome to the Industrial Technology Institute (ITI)

 

The pioneer Scientific Research & Development organization in Sri Lanka. We are the successor to Ceylon Institute of Scientific and Industrial Research (CISIR) and comes under the purview of the Ministry of Industries  and is accredited as per ISO 17025:2017 and conforms to ISO 9001:2015 Quality Management Standards.

 

Performance 2010-2022               
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 DRKALAPA

 

Dr. Kalpa W. SAMARAKOON

 

Research Scientist
Herbal Technology Section

 

Qualifications

Ph.D. (Marine Biotechnology), Jeju National University, South Korea, 2014

M.Sc. (Applied Organic Chemistry) - University of Colombo, 2010

B.Sc. (Chemistry) – University of Colombo, 2004

 

Contacts

Tel: 94 011 2379800     Ext:334     E mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

Specialized Fields

  • Natural Product Chemistry
  • Organic Chemistry
  • Marine Biotechnology
  • Biochemistry and Pharmacology

 

Interest Areas       

  • Isolation, purification and characterization of novel functional ingredients from the marine natural bio-resources
  • Pharmacological, nutraceutical and cosmeceutical prospects of the isolated bioactive components are evaluating with the advanced and recent biotechnological and chemical tools

 

Publications

Peer-reviewed  original research  publications (SCI & SCIE)

 

  • Samarakoon KW,  Nam OK, Ko JY, Lee JH, Kang MC, Kim D, Lee JB & Jeon YJ. Purification and identification of novel angiotensin-I converting enzyme (ACE) inhibitory peptides from cultured marine microalgae (Nannochloris oculata) protein hydrolysate. Journal of Applied Phycology 25: 1595-1606 (2013)
  • Samarakoon KW, Ko JY, Shah MMR, Lee JH, Nam OK, Lee JB & Jeon YJ. In vitro studies of anti-inflammatory and anticancer activities of organic solvent extracts from cultured marine microalgae. ALGAE 28: 111-119 (2013).
  • Samarakoon KW, Lee JH, Dilip de Silva E, Kim UA, Wijesundara RLC, Lakmal, HHC & Jeon YJ. Bioactivity evaluation of organic solvent extractions of Ganoderma lucidum: a Sri Lankan BasidiomyceteJournal of the National Science Foundation of Sri Lanka 41(3):249-257(2013).
  • Samarakoon KW, Cha SH, Lee JH & Jeon YJ. The growth, innate immunity and protection against H2O2-induced oxidative damage of a chitosan-coated diet in the olive flounder (Paralichthys olivaceus). Journal of Fisheries and Aquatic Science 16(3):149-158 (2013).
  • Samarakoon K, Senevirathne M, Lee WW, Kim YT, Kim JI, Oh MC & Jeon YJ. Antibacterial effect of citrus press-cakes dried by High speed and far-infrared radiation drying methods. Nutrition Research and Practice 6(3): 187-194 (2012). 
  • Samarakoon KW, Ko JY, Le, JH, Nam OK, Jeon YJ. Apoptotic anticancer activity of a novel fatty alcohol ester isolated from cultured marine diatom, Phaeodactylum tricornutum, Journal of Functional Foods 6: 231-240 (2014).
  • Samarakoon KW, Lakmal HHC, Kim SY, Jeon YJ. Electron spin resonance spectroscopic measurement of antioxidant activity of organic solvent extracts derived from the methanolic extracts of Sri Lankan Thebu leaves (Costus speciosus)Journal of National Science Foundation of Sri Lanka (2014) (In press)
  • Samarakoon KW, Chaminda Lakmal HH, Lee WW, Lee JH, Abethunga DTU, Lee HS, Jeon YJ. In vitro anticancer and antioxidant effects of some selected Sri Lankan Marine algae. Journal of National Science Foundation of Sri Lanka (2014) (In press)
  • Lee JH, Ko JY, Samarakoon KW, Oh JY, Heo SJ, Kim CY, Nah JW, Jang MK, Lee JS, Jeon YJ. Preparative isolation of sargachromanol E from Sargassum siliquastrum by centrifugal partition chromatography and its anti-inflammatory activity. Food and Chemical Toxicology 62: 54-60 (2013).
  • Kang MC, Kim SY, Kim YT, Kim EA, Lee SH, Ko SC, Wijesinghe WAJP, Samarakoon KW, Kim YS, Cho JH, Su J & Jeon YJ. In vitro and in vivo antioxidant activities of polysaccharide purified from Aloe vera (Aloe barbadensis) gel. Carbohydrate Polymers 99: 365-371(2014).
  • Kang N, Ko SC, Samarakoon K, Kim EA, Kang MC, Lee SC, Kim J, Kim YT, Kim JS, & Jeon YJ. Purification of Antioxidative Peptide from Peptic Hydrolsates of Mideodeok (Stela clava) Flesh Tissue. Food Science and Biotechnology22: 541-547(2013).
  • Kang MC, Kang SM, Ahn G, Kim KN, Kang N, Samarakoon KW, Oh MC, Lee JS & Jeon YJ. Protective effect of a marine polyphenol, dieckol against carbon tetrachloride-induced acute liver damage in mouse. Environmental Toxicology and Pharmacology 35: 517-523 (2013).
  • Ko JY, Lee JH, Samarakoon KW, Kim JS & Jeon YJ.  Purification and determination of two novel antioxidant peptides from flounder (Paralichthys olivaceus) fish using digestive peptidases. Food and Chemical Toxicology52: 113-120 (2013).
  • Shah MMR, Samarakoon KW, Ko JY, Lee JH, Jeon YJ, Lee JB. Potentiality of   benthic dinoflagellate cultures and screening of their bioactivities in Jeju Island, Korea, African Journal of Biotechnology 13(6): 792-805(2014).
  • Kim KN, Kim JH, Yoon WJ, Yang HM, Heo SY, Ko JY, Roh SW, Jeon YJ, Kang SM, Heo SJ, Samarakoon KW, Kim DS, Kim D.  Inhibitory effects of Sargassum patens on Inflammation and Melanogesis. International Journal of Pharmacology. DOI: 10.3923/ijp.2013.
  • Sharma N, Samarakoon KW, Gyawali R, Park YH, Lee SJ, Oh SJ, Lee TH, Jeong DK. (2014). Evaluation of the Antioxidant, an anti-inflammatory and anticancer activity of Euphorbia hirta ethanolic extracts. Molecules19, 14567-14581.

Peer-reviewed  International review articles.

  • Samarakoon KW & Jeon YJ.  Bio-functionalities of proteins derived from marine algae-A review. Food Research International48: 948-960 (2012).
  • Samarakoon KW, Marine Biotechnology on algae derived proteins and bio-functional effects. Journal of Animal Research2: 121-126 (2012).
  • Samarakoon KW, Elvitigala DAS, Lakmal HHC, Jeon YJ. Future prospects and health benefits of functional ingredients from marine bio-resources: A review. Journal of Fisheries and Aquatic Science (2014) (In press).

 

Peer-reviewed  International book chapters

  • Samarakoon KW & Jeon YJ. Recovery of proteins and their bio- functionalities from marine algae, Chapter 12, Marine Proteins and Peptides: Biological Activities and Applications, John Wiley & Sons Ltd, West Sussex, PO198SQ, UK. 03/ 05/2013, pp. 253-269 (2013).
  • Samarakoon KW, Chaminda Lakmal HH, Jeon YJ. Preparation of useful components from marine algal by-products and their applications, Chapter 28. Advanced in Seafood Processing By-Products: Trends and Applications.  DOI 10.1007/978-1-4614-9590-1_26, (2014).
  • Samarakoon K.W., Elvitigala D.A.S., Jeon Y.J Marine-derived pharmaceuticals and future prospects, Application of Marine Biotechnology, Chapter 41, Springer Handbook of Marine Biotechnology (2014) DOI: 10.1007/978-3-642-53971-8_41, pp.957-968.
    • Lakmal H.H.C., Samarakoon K.W., Jeon Y.J. Enzyme-assisted extraction to prepare bioactive peptides from microalgae. Chapter 18, Marine Algae Extracts : Processes, Products, and Applications,  DOI: 10.1002/9783527679577, pp.305-318
  • Samarakoon K.W., Lakmal H.H.C., Jeon Y.J. The Prospects of Marine Organisms and their Pharmacological and Nutraceutical Aspects. Chapter, Volume 42, Recent Progress in Medicinal Plants, Studium Press India Pvt Ltd. (2014) (Submitted)

 

Articles in Magazines

  • Kalpa W. Samarakoon. Natural Products from Sri Lankan Marine Algae and their Future Prospects.Sath samudura Magazine 2014, Worlds Ocean Day,Sri Lanka.
  • Kalpa W. Samarakoon, You-Jin Jeon. Marine algae derived proteins and their bio-functional effects.  RESONANCE 2013 Edition, Chemical Society, University of Colombo, pp 105-108.
  • Kalpa W. Samarakoon, Md. Mahfuzur Rahman Shah. Microalgae biomass culturing and their biochemical analysis. Jeju Sea Grant Project 2013. Jeju National University, Jeju, Republic of Korea.

 

Manuscript in progress

  • Shah MMR, Samarakoon KW, An SJ, Jeon YJ, Lee JB. Growth characteristics of three benthic dinoflagellates in photobioreactor and their antioxidant properties from Jeju Island, Korea.
  • Samarakoon KW, Silva ED, Wijesundara RLC, Jeon YJ. Isolation of a novel lanostane-type triterpenoid from Ganoderma luciderm through the screening of antimicrobial activities of some selected Sri Lankan terrestrial fungi. 
  • Samarakoon K.W., R. G. P. T. Jayasooriya, H.H.C. Lakmal, M. G. Dilshara, Y.J. Jeon Caspase-3-mediated apoptosis through inhibition of cell proliferation in leukemia cancer cells (HL-60) and anti-inflammatory effects in vitro from Thebu leaf, Costus speciosus (Koen.) Sm. (2015)

 

Other Research Communications :

 

  • Samarakoon K.W. (2014). Bioactive Natural Products from Cultured Marine Microalgae and Sri Lankan Marine Algae, Thesis submitted for the partial fulfillment of the PhD in Marine Life Sciences. Jeju National University, Republic of Korea.
  • Samarakoon KW. (2009). Isolation of Biological active compounds of some selected terrestrial Fungi of Sri Lanka, Thesis submitted for the partial fulfillment of the M.Sc in Applied Organic Chemistry,University of Colombo.
  • Kalpa W. Samarakoon. Natural Products from Sri Lankan Marine Algae and their Future Prospects. Sath Samudura Magazine 2014, World Oceans Day, Sri Lanka.
  • Kalpa W. Samarakoon, You-Jin Jeon. Marine algae derived proteins and their bio-functional effects.  RESONANCE 2013 Edition, Chemical Society, University of Colombo, pp 105-108.
  • Kalpa Samarakoon, Md. Mahfuzur Rahman Shah. Microalgae biomass culturing and their biochemical analysis. Jeju Sea Grant Project 2013. Jeju National University, Jeju, Republic of Korea.

 

 

Awards

Poster Award: 

Sanjeewa K.K.A. Samarakoon KW, Ko JY, Le, JH, Nam OK, Jeon YJ.  Apoptotic anticancer activity of a novel fatty alcohol ester isolated from cultured marine diatom, Phaeodactylum tricornutum. The 6th International Conference on Food Factors (ICOFF- 2015) 25th November 2015 in Seoul, South Korea

Lectures & presentations

Lectures and Oral Presentations:

 

  • Kalpa W. Samarakoon, H. H.C. Lakmal, E D de Silva, D T U Abeytunga, C Nanayakkara, You-Jin Jeon. Electron spin resonance, ABTS+ on-line HPLC and in vitro antioxidant activities of Sri Lankan brown alga: Padina commersonii. Sri Lanka Association for the Advancement of Science (SLAAS), Proceeding of the 71st Annual Sessions 2015, Abstract Number 605/E2.
  • Kalpa W. Samarakoon, H. H.C. Lakmal, D.T.U. Abethunga, You-Jin Jeon. Isolation of Bioactive Natural Products from Some Selected Sri Lankan Seaweeds. Abstract Number 50, Second National Symposium on Marine Environment 2015, by MEPA 18th – 19thNovember 2015 at Sri Lanka Foundations, Colombo 7.
  • Kalpa W. Samarakoon, H. H.C. Lakmal, You-Jin Jeon. Determination and Isolation of marine derived Secondary Metabolites in Sri Lankan Marine Algae through Electron Spin Resonance, ABTS+ on-line HPLC and High performance Centrifugal Partition Chromatography (HPCPC), ITI Biennial Research Symposium 2015, Theme: Science, Technology and Innovation for Knowledge based Economy, 16th – 17th November 2015 at ITI, Colombo 7.
  • Kalpa W. Samarakoon, H. H.C. Lakmal, Prasad Tharanga Jayasooriya, You-Jin Jeon. Inhibitory Effect on Human Leukemia (HL-60) Cancer Cell Proliferation via Caspase-3 mediated Apoptosis by Costus speciosus (Koen.) Sm. Leaf Extract. The institute of Biology Sri Lanka, Proceeding of the 35th Annual Sessions 2015, Abstract Number 3-04
  • Kalpa W. Samarakoon, You-Jin Jeon. Evaluation of antioxidant, anti-inflammatory and anticancer activity of solvent extracts from Sri Lankan Thebu leaf (Costus speciosus). Sri Lanka Association for the Advancement of Science (SLAAS), Proceeding of the 70th Annual Sessions 2014, Abstract Number 606/E2.
  • Kalpa W. Samarakoon, E. Dilip de Silva, You-Jin Jeon. In vitro anti-inflammatory, anticancer, and antioxidant effects from a terrestrial basidiomycete; Ganoderma lucidum. The institute of Biology Sri Lanka, Proceeding of the 34th Annual Sessions 2014, Abstract Number 2-12, 52.
  • Samarakoon, K., Ko, J.Y., Lee, J.H. & Jeon, Y.J. Isolation of bioactive compounds from cultured marine microalgae (blue green algae and diatom) through the enzymatic and organic solvent extractions. Kongju National University, Chungcheongnam-do, South Korea, 24thOctober 2012.
  • Samarakoon, K., Cha, S. H. & Jeon, Y. J. Protective effect against H2O2-induced oxidative damage on olive flounder (Paralichthys olivaceus) fed with chitosan-coated diet in aquaculture. International Conference on Fisheries & Marine Science (Marine Fish 2012), 23-24 August 2012, Negombo, Sri Lanka.
  • Samarakoon, K., Cha, S. H. & Jeon, Y. J. Growth, Innate immunity and protective effect of (Paralichthys olivaceus) fed chitosan-coatd diet in aquaculture. 10th AFAF, CAA4 2013, Blue waters and Green fisheries. 30th April-4th May 2013, The Ocean Resort Hotel, Yeosu, Korea.

Poster presentations: 

  • H. H. Chaminda Lakmal, Kalpa W. Samarakoon, Ju-Young Ko, Ji-Hyeok Lee, You-Jin Jeon. A novel fatty alcohol ester isolated from the cultured marine diatom. Phaeodactylum tricornutum and apoptosis induced anticancer activity. Innovations in Food Science for Human well-being. Annual Meeting Korean Society of Food Science and Technology. 28th -30th August 2013, Cheonan Arts center, South Korea.
  • Ju-Young Ko, Ji-Hyeok Lee, Kalpa W. Samarakoon, You-Jin Jeon. Protective effect of aquaculture flounder fish-derived peptides against oxidative stress in Zebrafish. The 10th Korean Zebrafish Meeting, July 5-6, 2013. KNU, Daegu, Korea.
  • Neelesh Sharma, Kalpa W. Samarakoon, Simrinder Singh Sodhi, Anh Nguyen Thai Quynh, Do Luong Huynh, Jeong Hyun Kim, Nameun Kim, Sung Jong Oh and Dong-Kee Jeong. In-vitro anti-oxidant and anti-inflammatory activity of ethanolic extract of an Asian hairy herbal plant. 27-28thJune, Korean Society of Animal Science, Jeju, Republic of Korea.
  • Kalpa W. Samarakoon, Ji-Hyeok Lee, Ju-Young Ko, You-Jin Jeon. Anti-inflammatory and anticancer activities from the cultured marine microalgae derived crude extracts. 10th AFAF, CAA4 2013, Blue waters and Green fisheries. 30th April-4thMay 2013, The Ocean Resort Hotel, Yeosu, Korea.
  • Kalpa W. Samarakoon, Ju-Young Ko, Ji-Hyeok Lee, O-Nam Kwon, You-Jin Jeon.  Angiotensin-I converting enzyme inhibitory peptides isolation and purification from the protein hydrolysate of microalgae, Nannochloris oculata. International Conference and Exhibition on Nutraceuticals and Functional Foods 2012, Dec. 1-6, 2012. Kailua- Kona,  Hawaii, USA
  • Kalpa Samarakoon, Ji-Hyeok Lee, Ju-Young Ko, Kwon-O.Nam, You-Jin Jeon, Apoptosis-inducing Anticancer and Anti-inflammatory compounds from a cultured marine diatom, Phaeoductylum tricornutum. The 17th Annual Meeting of Korean Society of Cancer Prevention,Nov. 9~10, 2012, Sungshin Women’s University (Woonjung Green Campus), Seoul, Korea.
  • Ji-Hyeok Lee , Ju-Young Ko, Kalpa W. Samarakoon, You-Jin Jeon, Anti-cancer activity of  pure new fucosteroid isolated from Hizikia fusiformis using centrifugal partition chromatography (CPC). The 17th Annual Meeting of Korean Society of Cancer Prevention, Nov. 9~10, 2012, Sungshin Women’s University (Woonjung Green Campus), Seoul, Korea.
  • Kalpa W.Samarakoon, Ju-Young Ko, Ji-Hyeok Lee, O-Nam Kwon, You-Jin Jeon. The characterization of angiotensin-I converting enzyme inhibitory peptides from marine microalgae. Quality of Life (QOL): Food Industry and Health, 2012 KFN International Symposium and Annual Meeting, Oct. 31-Nov. 2, 2012, ICC Jeju, Jeju, Korea.
  • Kalpa W.Samarakoon, Ju-Young Ko, Ji-Hyeok Lee, O-Nam Kwon, You-Jin Jeon. Identification of novel antihypertensive peptides from the protein hydrolysates of Nannocloris oculata. Algae and the Human Future, The 26th meeting of the Korean Society of Phycology, October 25-26th2012, Gangneung, Ganwon-do, Korea.
  • Md. Mahfuzur Rahman Shah, Kalpa Samarakoon, et al. Biomass production and screening of anti-inflammatory, anticancer, and antioxidant  activities from benthic dinoflagelates of Jeju Island, Korea. Algae and the Human Future, The 26th meeting of the Korean Society of Phycology, October 25-26th2012, Gangneung, Ganwon-do, Korea.
  • Ju-Young Ko, Ji-Hyeok Lee, Kalpa Samarakoon, You-Jin Jeon. Anti-cancer activity of purified compounds isolated from Hizikia fusiformis using centrifugal partition chromatography (CPC). Algae and the Human Future, The 26th meeting of the Korean Society of Phycology, October 25-26th2012, Gangneung, Ganwon-do, Korea.
  • Samarakoon, K., Ko, S.C., Jeon, Y. J. Isolation and purification of angiotensin-I converting enzyme (ACE) inhibitory peptides from marine microalgae. International Conference on Fisheries & Marine Science (Marine Fish 2012), 23-24 August 2012, Negombo, Sri Lanka.
  • Samarakoon, K., Senevirathne, M. & Jeon, Y. J. The effect of antibacterial activity of dried citrus press-cakes against fish and food-related pathogenic bacteria. A New Era  of Biotechnology and Bioeconomy, 2012 International Symposium & Annual Meeting,June 27-29, 2012, BEXCO, Busan, Korea.
  • Samarakoon, K. W., Wijesinghe, W. A. J. P. & Jeon, Y. J. Biologically active  proteins from marine algae for bio-functional applications. Fishery Sciences Association of Korea (FSAK), November 18-19, 2011, BEXCO, Busan, Korea.
  • Wijesinghe, W. A. J. P., Samarakoon, K., Lee, W. W. & Jeon, Y. J. Use of enzymatic cell wall degradation  and release of bioactive components from seaweeds.  Fishery Sciences Association of Korea (FSAK), November 18-19, 2011, BEXCO, Busan, Korea.
  • Samarakoon, K.W., Wijesinghe, W. A. J. P., Athukorala, Y. & Jeon, Y. J. Anticoagulant activity of fucoidan purified from Ecklonia cava in wistar rats. International Conference of Food Factors (ICoFF2011), November 20-23, 2011, Taipei, Taiwan.
  • Samarakoon, K. W., Wijesinghe, W. A. J. P., Athukorala, Y. & Jeon, Y. J. Anticoagulant activity of fucoidan purified from Ecklonia cava in wistar rats. The 6th Asian Pacific Phycological Forum (APPF), October 9-14, 2011, Yeosu, Korea.

 

Major Projects Undertake

Project in progress:

 

  • Undertaken the project of ‘Establishment of cell culture facility at ITI’ as a Treasure Grant (TG/15/106) for 2014/2015. 
  • Undertaken the Collaborative Research Project (FP-117) titled ‘Investigation of Sri Lankan Marine Algae’ between Korea Institute of Ocean Science & Technology (KIOST) and Industrial Technology Institute (ITI). 
  • Co-supervising the project of Bioassay guided fractionation and isolation of bioactive natural compounds from Bryophyta.
  • Quantification of active ingredient in paracetamol samples from Market Basket Study (TG/00/04).

 

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